PricheePharma

Most advances in the world of drug delivery systems in particular to chronic Cardiovascular Diseases are transpired. In this stipulation, the entire pharmaceutical Industry is binding themselves for the newer drug deliveries with their own Research and Development.

          Cell-selective targeted drug delivery has emerged as one of the most significant areas of biomedical engineering research, to optimize the therapeutic efficacy of a drug by strictly localizing its pharmacological activity to a path physiologically relevant tissue system. These concepts have been applied to targeted drug delivery to the cardiovascular system. Certain devices are used for drug delivery to the cardiovascular system.

            New cell-based therapeutic strategies are being developed in response to the shortcomings of available treatments for heart disease. Potential repair by cell grafting or mobilizing endogenous cells holds particular attraction in heart disease, where the meager capacity for cardiomyocyte proliferation likely contributes to the irreversibility of heart failure.
           Cell therapy approaches include attempts to reinitiate cardiomyocyte proliferation in the adult, conversion of fibroblasts to contractile myocytes, conversion of bone marrow stem cells into cardiomyocytes, and transplantation of myocytes or other cells into injured myocardium.

 Cell-Selective targeted drug delivery systems that fortify R&D pipelines and enhance compounds by:                                                                 
         • Enhancing bioavailability via bypassing first pass metabolism
         • Minimizing pharmaco-kinetic peaks and troughs
         • Improving tolerability and dosing
         • Increasing patient compliance
         • Continuous delivery

Major break throughs are:
       Induction of the proliferation of cardiomyocytes at specific sites of Heart plays pivot role in curing the CVD and Cell-mediated immune modulation for chronic heart disease is useful inventions.

       Cell transplantation of Myoblasts for treatment of congestive heart failure and Injection of adult stem cells for congestive heart failure are astounding.

In conclusion, our Cell-selective targeted drug delivery system showed promising results in enhancing the treatment of selected areas of the Cardio vascular diseases and controlling the dose applied.